Association between body positioning and gastroesophageal reflux in paediatric age

Paolo Quitadamo1,2, Renato Tambucci3,4, Annalisa Alessandrella1

  • 1Department of Translational Medical Science, Section of Pediatrics, "Federico II" University of Naples, Naples, Italy.

Insights

Postural measures for gastroesophageal reflux (GER) in children and adolescents are often recommended without strong evidence. This study found that upright positions significantly increase reflux episodes and slow acid clearance compared to recumbent positions.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Motility Disorders

Background:

  • Postural interventions are commonly advised for managing gastroesophageal reflux (GER) symptoms in pediatric populations.
  • However, robust scientific evidence supporting the efficacy of specific body positions for GER management in children and adolescents remains limited.

Purpose of the Study:

  • To investigate the impact of upright versus recumbent body positions on gastroesophageal reflux (GER) episodes in pediatric patients.
  • To provide data-driven insights into the effectiveness of postural management for GER in children and adolescents.

Main Methods:

  • A retrospective analysis of pH-impedance parameters was conducted on 187 pediatric patients (mean age ~7 years) referred for GER symptoms.
  • Data were collected from two Italian hospitals between September 2016 and September 2018.
  • Patient data were analyzed separately for upright and recumbent positions.

Main Results:

  • Acid exposure time remained consistent regardless of body position (P > .05).
  • The mean number of reflux episodes per hour was significantly higher in the upright position (2.99) compared to the recumbent position (1.21) (P < .05).
  • Mean esophageal acid clearance time was notably shorter in the upright position (44.4 seconds) versus the recumbent position (93.4 seconds) (P < .05).

Conclusions:

  • Pediatric patients experience more frequent reflux episodes and prolonged acid exposure in upright positions, likely due to awake-related transient lower esophageal sphincter relaxations.
  • These findings offer novel evidence to refine postural recommendations for managing GER in children and adolescents.
Abstract

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