Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood and Nerve Supply to the Kidney01:18

Blood and Nerve Supply to the Kidney

3.9K
The kidneys are vital organs responsible for filtering and cleaning blood, removing waste products, and regulating electrolyte levels. To perform these essential functions, they require a constant and robust blood supply.
Bloody Supply to the Kidneys:
The kidneys receive their blood supply from the renal arteries, which branch off from the abdominal aorta—the main artery supplying the abdomen and lower body. The renal arteries enter the kidneys at the hilum, a notch on the medial side of...
3.9K
Nervous System01:21

Nervous System

3.2K
The nervous system coordinates body functions through its complex network of nerve cells, enabling sensation and movement. It is divided into two primary parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is composed of the brain and the spinal cord. The brain acts as the body's control center, processing sensory information and coordinating responses. The spinal cord functions as a major signaling pathway for the brain and the rest of the body.
3.2K
Glial Cells01:04

Glial Cells

92.9K
Overview
92.9K
Peripheral Nervous System: Ganglia and Nerves01:24

Peripheral Nervous System: Ganglia and Nerves

4.8K
The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
The nerve is a bundle of axons that serves as the communication highway in the PNS. Each nerve is ensheathed in a protective layer of connective tissue called the epineurium. This outermost layer safeguards the nerve and supports the...
4.8K
Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

6.3K
Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...
6.3K
Veins of Head and Neck01:19

Veins of Head and Neck

5.0K
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
5.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Geriatric brain tumor management part II: Glioblastoma multiforme.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2019
Same author

Geriatric brain tumor management part I: Meningioma.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2019
Same author

Treatment of Asymptomatic Meningioma With Gamma Knife Radiosurgery: Long-Term Follow-up With Volumetric Assessment and Clinical Outcome.

Neurosurgery·2019
Same author

Radiation dose to neuroanatomical structures of pituitary adenomas and the effect of Gamma Knife radiosurgery on pituitary function.

Journal of neurosurgery·2019
Same author

Repeat Stereotactic Radiosurgery for Progressive or Recurrent Vestibular Schwannomas.

Neurosurgery·2018
Same author

Adaptive Hybrid Surgery: Paradigm Shift for Patient-centered Neurosurgery.

Rambam Maimonides medical journal·2018

Related Experiment Video

Updated: Jan 5, 2026

A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay
08:26

A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay

Published on: April 12, 2018

8.5K

Nervous System Hemangiopericytoma.

Or Cohen-Inbar1,2

  • 1Department of Neurological Surgery, University of Pittsburgh, Cumberland, MD, USA.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|October 15, 2019
PubMed
Summary
This summary is machine-generated.

Management of central nervous system (CNS) hemangiopericytomas (HPCs) involves surgery and radiotherapy for local control. While surgery improves survival, advanced treatments like stereotactic radiosurgery (SRS) offer safe tumor volume control for select lesions.

Keywords:
Adoptive hybrid surgeryEBRTHemangiopericytomaStereotactic radiosurgery

More Related Videos

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
03:53

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas

Published on: October 10, 2025

384
Author Spotlight: Imaging Pericytes Post-Subarachnoid Hemorrhaging in Rodents
05:11

Author Spotlight: Imaging Pericytes Post-Subarachnoid Hemorrhaging in Rodents

Published on: August 18, 2023

1.6K

Related Experiment Videos

Last Updated: Jan 5, 2026

A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay
08:26

A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay

Published on: April 12, 2018

8.5K
An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
03:53

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas

Published on: October 10, 2025

384
Author Spotlight: Imaging Pericytes Post-Subarachnoid Hemorrhaging in Rodents
05:11

Author Spotlight: Imaging Pericytes Post-Subarachnoid Hemorrhaging in Rodents

Published on: August 18, 2023

1.6K

Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Radiation Oncology

Background:

  • Central nervous system (CNS) hemangiopericytomas (HPCs) are rare, locally aggressive tumors with risks of recurrence and metastasis.
  • Complete resection is ideal but often precluded by patient or tumor factors.
  • Current management strategies for HPCs require further elucidation.

Purpose of the Study:

  • To review the current evidence on managing CNS hemangiopericytomas.
  • To discuss the roles of microsurgical resection, external beam radiotherapy (EBRT), and stereotactic radiosurgery (SRS).
  • To explore systemic treatments including chemotherapy and immunotherapy for upfront or recurrent HPCs.

Main Methods:

  • Literature review of studies on CNS hemangiopericytoma management.
  • Analysis of treatment outcomes including overall survival (OS) and progression-free survival (PFS).
  • Evaluation of local tumor control, metastasis development, and treatment safety.

Main Results:

  • Surgery alone or with EBRT significantly improves OS and PFS compared to biopsy alone.
  • EBRT and SRS are effective for local tumor control and preserving neurologic function but do not impact metastasis.
  • Single-session SRS is effective for small lesions (<2 cm diameter, <10 cm3 volume) with high doses (>15 Gy).
  • Systemic therapies for HPCs have shown limited success.

Conclusions:

  • Microsurgical resection is the primary treatment for CNS HPCs when feasible.
  • EBRT and SRS play crucial roles in local control and are valuable adjuncts or alternatives.
  • Further research into effective systemic therapies is warranted for advanced or recurrent disease.