Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accessory Structures of the Eye01:17

Accessory Structures of the Eye

3.2K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
3.2K
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

8.6K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.6K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

915
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
915
Glaucoma: Overview01:25

Glaucoma: Overview

1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

3.8K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
3.8K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aerobic Exercise and Subthreshold Depressive Symptoms in Adolescents: Secondary Analysis of a Randomized Clinical Trial.

JAMA network open·2026
Same author

Time-resolved single-nucleus profiling of inter- and intracellular signaling in optic nerve injury: From the hyperacute phase to the acute phase.

Neural regeneration research·2026
Same author

Astrocytic FDX1 Contributes to Copper Dyshomeostasis-associated Synaptic Dysfunction in Depression and Is Modulated by Exercise.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Intravitreal delivery of NGF-chitosan hydrogel confers retinal ganglion cell protection and visual function recovery in experimental glaucoma.

Bioactive materials·2026
Same author

Repeated exposure to the smell of innate fear, trimethylthiazoline, promotes fear habituation and hippocampal cell proliferation in rats.

Stress (Amsterdam, Netherlands)·2026
Same author

Beyond antioxidation: Retinal neuroprotection by Lycium barbarum polysaccharides via multiple signaling pathways.

Neural regeneration research·2026

Related Experiment Video

Updated: Jan 5, 2026

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

6.6K

Adiponectin, exercise and eye diseases.

Hong-Ying Li1, Xi Hong2, Qian-Qian Cao2

  • 1Department of Anatomy, Medical School, Jinan University, Guangzhou, PR China; Guangdong-Hongkong-Macau Institute of CNS Regeneration, Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Jinan University, Guangzhou, PR China; Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, PR China.

International Review of Neurobiology
|October 15, 2019
PubMed
Summary
This summary is machine-generated.

Adiponectin, an adipokine, shows neuroprotective effects in neurodegenerative diseases and eye conditions. Exercise may enhance this protection in the eyes by increasing adiponectin levels, warranting further research.

Keywords:
AdipokinesAdiponectinExerciseEye diseasesProtection

More Related Videos

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
04:36

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

1.5K
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

3.4K

Related Experiment Videos

Last Updated: Jan 5, 2026

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

6.6K
Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression
04:36

Author Spotlight: Understanding Retinal Vessel Resilience and Disease Progression

Published on: January 12, 2024

1.5K
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

3.4K

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Endocrinology

Background:

  • Adiponectin, an adipokine, demonstrates neuroprotective properties relevant to neurodegenerative diseases.
  • Adiponectin receptors (AdipoRs) are present in retinal cells, suggesting a role in ocular health.
  • Adiponectin circulates in the bloodstream, crosses the blood-brain barrier, and is produced locally in the brain and retina.

Purpose of the Study:

  • To review the protective effects of adiponectin in various eye diseases.
  • To explore the potential of exercise in modulating adiponectin levels for ocular protection.

Main Methods:

  • Literature review of published studies on adiponectin and eye diseases.
  • Analysis of adiponectin's systemic and local production pathways.
  • Examination of exercise's known effects on adiponectin levels.

Main Results:

  • Adiponectin has demonstrated protective effects in several neurodegenerative conditions.
  • Evidence suggests adiponectin plays a role in retinal cell function and protection.
  • Exercise is known to increase systemic and central nervous system adiponectin, but its effect on ocular adiponectin is unconfirmed.

Conclusions:

  • Adiponectin, via its receptors, is implicated in protecting against eye diseases.
  • Exercise may offer a potential therapeutic strategy for eye conditions by increasing adiponectin.
  • Further investigation is required to confirm exercise's impact on ocular adiponectin and its therapeutic benefits.