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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
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Screening for diabetes in asymptomatic children: A simple and efficient method.

Wan-Chen Wu1, Hung-Yuan Li1, Chuan-Chi Chiang2

  • 1Department of Internal Medicine, National Taiwan University Hospital, Taipei, 100, Taiwan.

Journal of the Formosan Medical Association = Taiwan Yi Zhi
|October 15, 2019
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Summary

A new screening method using urinalysis and risk factors can efficiently identify type 2 diabetes in children. This simple approach aids early detection in schools, even for asymptomatic cases.

Keywords:
ChildrenDiabetesScreening

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Area of Science:

  • Pediatrics
  • Endocrinology
  • Public Health

Background:

  • Type 2 diabetes is a growing concern in pediatric populations.
  • Many children with type 2 diabetes are asymptomatic, necessitating effective screening.
  • Current professional recommendations often require physician involvement, limiting accessibility.

Purpose of the Study:

  • To develop a simple and efficient screening method for identifying diabetes in children.
  • To address the need for a non-physician-led screening approach in schools.

Main Methods:

  • A nationwide survey of 2,270,496 seventh-grade students.
  • Implementation of three distinct screening methods.
  • Sequential urinalysis followed by fasting blood tests for students with abnormal results.

Main Results:

  • Method C, involving urinalysis plus risk factor assessment (overweight or family history), proved simple and effective.
  • 0.10% of boys and 0.16% of girls were recommended for blood tests.
  • Diabetes was diagnosed in 7.0% of boys and 6.7% of girls who underwent blood testing.

Conclusions:

  • Urinalysis screening combined with risk factor evaluation is a practical and efficient strategy for detecting childhood diabetes.
  • This method facilitates early identification of diabetes in school settings.
  • The approach offers a viable alternative to physician-dependent screening protocols.