Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Central opioids: a possible role in parturition?

G Leng, S Mansfield, R J Bicknell

    The Journal of Endocrinology
    |August 1, 1985
    PubMed
    Summary

    Opioid signaling influences birth spacing in rats, with naloxone shortening delivery intervals. Stressful environments did not alter this opioid effect on parturition timing.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comparing full-field data from structural components with complicated geometries.

    Royal Society open science·2021
    Same author

    From the National Health Service to local government: perceptions of public health transition in England.

    Public health·2019
    Same author

    Effects of lateral olfactory tract stimulation on Fos immunoreactivity in vasopressin neurones of the rat piriform cortex.

    Journal of neuroendocrinology·2017
    Same author

    Evidence-based medicine meets democracy: the role of evidence-based public health guidelines in local government.

    Journal of public health (Oxford, England)·2017
    Same author

    Effect of Melanotan-II on Brain Fos Immunoreactivity and Oxytocin Neuronal Activity and Secretion in Rats.

    Journal of neuroendocrinology·2016
    Same author

    Measuring Oxytocin and Vasopressin: Bioassays, Immunoassays and Random Numbers.

    Journal of neuroendocrinology·2016

    Area of Science:

    • Neuroendocrinology
    • Reproductive Physiology

    Background:

    • Opioid innervation of the neurohypophysis significantly impacts oxytocin release.
    • Oxytocin plays a crucial role in the physiological processes of parturition.

    Purpose of the Study:

    • To investigate the role of opioid signaling in regulating parturition timing.
    • To determine if stress modulates the opioid influence on birth spacing during parturition.

    Main Methods:

    • Pregnant rats received subcutaneous minipumps delivering either naloxone or saline.
    • Parturition time-course was monitored, with some groups subjected to environmental stress during birth.

    Main Results:

    • Naloxone treatment significantly shortened the interval between successive births compared to saline controls.

    Related Experiment Videos

  • Environmental stress altered parturition time-course but did not affect the difference between naloxone and saline groups.

    • Conclusions:

    • Opioid modulation of oxytocin release is implicated in spacing successive births during normal parturition.
    • The observed opioid effect on birth spacing is not dependent on the tested stressful environment.