[Meningitis due to infection with Borrelia hispanica]

Jennie Heida1,2, Andreas van Arkel3, Jaco J Verweij3

  • 1Elisabeth-TweeSteden Ziekenhuis, afd. Neurologie, Tilburg.

Insights

Tick-borne relapsing fever, caused by Borrelia bacteria transmitted by ticks, presents with recurrent fevers. Early antibiotic treatment, like ceftriaxone, is crucial for recovery and preventing severe illness.

Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Neurology

Background:

  • Tick-borne relapsing fever (TBRF) is an infection caused by Borrelia bacteria transmitted through tick bites.
  • The disease is characterized by recurring high fever episodes and non-specific symptoms.

Observation:

  • A 20-year-old woman presented with recurrent fever, headache, and vomiting after traveling to Morocco.
  • Cerebrospinal fluid analysis revealed pleocytosis, initially suggesting viral meningitis.
  • Borrelia species were identified via 16S-rRNA PCR, confirming TBRF.

Findings:

  • The patient received a two-week course of intravenous ceftriaxone.
  • Symptoms gradually improved following antibiotic treatment.

Implications:

  • Prompt diagnosis and antibiotic therapy are essential for managing TBRF and preventing severe outcomes.
  • Clinicians should consider TBRF in patients with recurrent fevers, especially after travel to endemic regions in Africa, America, or the Middle East.

Related Concept Videos

Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
517
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
832
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
3.4K
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
320