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Left atrium: a forgotten biomarker and a potential target in cardiovascular medicine

Riccardo M Inciardi1, Andrea Rossi

  • 1Division of Cardiology, Department of Medicine, University of Verona, Verona, Italy.

Journal of Cardiovascular Medicine (Hagerstown, Md.)
|October 15, 2019
PubMed

Insights

Left atrium analysis is crucial for diagnosing and predicting cardiovascular disease. Assessing its structure and function helps identify high-risk individuals, guiding treatment strategies for better patient outcomes.

Area of Science:

  • Cardiovascular Medicine
  • Cardiac Imaging
  • Clinical Cardiology

Background:

  • Left atrium structural and functional remodeling is a sensitive indicator of cardiovascular risk.
  • Remodeling is observed in various conditions including atrial fibrillation, heart failure, ischemic heart disease, and valvular heart disease.
  • Left atrium analysis offers valuable insights into subclinical and clinical cardiovascular disease.

Purpose of the Study:

  • To review methods for assessing left atrium structure and function.
  • To highlight the role of left atrium analysis in identifying cardiovascular disease.
  • To emphasize its utility in providing prognostic information for risk stratification.

Main Methods:

  • Review of current methodologies for evaluating left atrium morphology and dynamics.
  • Synthesis of evidence linking left atrium assessment to cardiovascular risk.
  • Focus on imaging techniques and functional assessments.

Main Results:

  • Left atrium analysis demonstrates significant clinical utility in diagnosis and prognosis.
  • It serves as a marker for detecting high-risk individuals across diverse cardiovascular conditions.
  • Provides additional prognostic data for stratifying patients.

Conclusions:

  • Left atrium assessment is a valuable tool in cardiovascular medicine.
  • It aids in early detection and risk stratification of patients with or at risk of cardiovascular disease.
  • Further research into left atrium as a therapeutic target is warranted.

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