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Updated: Jan 5, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Apolipoprotein L1 (APOL1) risk variant toxicity depends on the haplotype background

Herbert Lannon1, Shrijal S Shah1, Leny Dias1

  • 1Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

Kidney International
|October 16, 2019
PubMed

Keywords:
APOL1chronic kidney diseasefocal segmental glomerulosclerosishaplotypetrypanosome

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