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Updated: Jan 5, 2026

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Published on: October 4, 2024
It's time to recognize the perichondrium
1Department of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA. tal.laor@childrens.harvard.edu.
Insights
The perichondrium, crucial for bone growth and health, is examined from fetal to childhood development. Its role in skeletal trauma, infection, and tumors is also reviewed.
Area of Science:
- Skeletal biology and radiology
Background:
- The perichondrium is a key structure at the chondro-osseous junction in growing bones.
- It is vital for normal skeletal development and implicated in various pathological conditions.
Purpose of the Study:
- To review the normal anatomy, function, and imaging characteristics of the perichondrium.
- To explore the perichondrium's appearance in skeletal trauma, infection, and tumors.
Main Methods:
- Literature review of the perichondrium's development and imaging.
- Analysis of radiologic findings in pathological conditions involving the perichondrium.
Main Results:
- Detailed illustration of perichondrial anatomy and function from fetal development through childhood.
- Review of the perichondrium's radiologic appearance in trauma, infection, and tumors.
Conclusions:
- The perichondrium is essential for skeletal development and its imaging is critical in diagnosing pediatric bone conditions.
- Understanding the perichondrium's role aids in managing skeletal trauma, infections, and tumors in children.
Abstract:
The perichondrium is a complex structure centered at the chondro-osseous junction of growing bones. It plays an important role in both normal skeletal development and in pathological conditions. This review illustrates the normal anatomy, function and imaging appearance of the perichondrium from fetal development to older childhood. The radiologic appearance of the perichondrium in skeletal trauma, infection and tumors in which it plays a role also are reviewed.
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