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Prolapse Repair Using Non-synthetic Material: What is the Current Standard?
Ricardo Palmerola1, Nirit Rosenblum2
1Departments of Urology and Obstetrics & Gynecology, New York University School of Medicine, 222 East 41st Street, 11th Floor, New York, NY, 10017, USA. ricardopalmerola@gmail.com.
Current Urology Reports
|October 16, 2019
Summary
Native tissue repair is a durable surgical option for pelvic organ prolapse. This approach avoids risks associated with synthetic mesh, offering an effective alternative for women.
Area of Science:
- Urogynecology
- Pelvic Floor Surgery
- Surgical Innovation
Background:
- Growing concerns regarding synthetic mesh in pelvic reconstructive surgery.
- Renewed interest in non-synthetic alternatives for pelvic organ prolapse (POP).
Purpose of the Study:
- To review current literature on POP repairs without synthetic mesh.
- To evaluate the efficacy and safety of native tissue repairs for POP.
Main Methods:
- Systematic review of existing studies on non-synthetic POP repairs.
- Analysis of randomized clinical trials and long-term follow-up data.
Main Results:
- Native tissue repairs demonstrate durable surgical outcomes for POP.
- Transvaginal native tissue repair is effective, without synthetic mesh risks.
- Recent trials show no clear advantage of synthetic mesh over native tissue repair.
- Long-term efficacy of native tissue repairs is good, especially when considering functional outcomes.
Conclusions:
- Native tissue repairs offer an efficacious alternative to synthetic mesh for POP.
- The FDA's 2019 action highlights risks associated with transvaginal mesh.
- Non-synthetic POP repairs provide a safe and effective surgical option.

