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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Methicillin resistant Staphylococcus aureus outbreak in a neonatal intensive care unit
Seema Irfan1, Imran Ahmed1, Farida Lalani2
1Department of Pathology & Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Abstract:
The global and national burden of communicable and noncommunicable diseases continues to rise, thus making access to Healthcare workers (HCWs) colonized with methicillin-resistant Staphylococcus aureus (MRSA) may pose transmission risk to vulnerable patients including neonates. This study reports an MRSA outbreak in a level-II neonatal intensive care unit (NICU) of a secondary care hospital in Pakistan. Once identified, an infection control team from the parent hospital visited the facility, risk factors were listed and infection control measures taken to control the outbreak. Screening cultures of NICU staff and environmental cultures from NICU were obtained for the presence of MRSA. Five neonates were positive for MRSA; one HCW was found to be colonized with MRSA, the antibiogram pattern of which matched with that of the outbreak strain. Decolonization of colonized HCWs and re-deployment from NICU to outpatient department were taken and the outbreak was declared over once no further MRSA cases were identified. Identification of an outbreak situation is the cornerstone for its control and multiple measures taken simultaneously help in curbing the outbreak. Although an epidemiological link was established with the HCW, a molecular link could not be proven.
Insights
Methicillin-resistant Staphylococcus aureus (MRSA) outbreaks in neonatal intensive care units (NICUs) pose risks. Prompt identification and control measures, including staff screening and decolonization, are crucial for patient safety.
Area of Science:
- Infectious Diseases
- Public Health
- Neonatology
Background:
- Rising global disease burdens necessitate robust infection control.
- Healthcare workers (HCWs) colonized with methicillin-resistant Staphylococcus aureus (MRSA) can transmit the pathogen to vulnerable patients.
- Neonatal intensive care units (NICUs) are high-risk environments for such transmissions.
Observation:
- An outbreak of MRSA occurred in a level-II NICU in Pakistan.
- Five neonates tested positive for MRSA.
- One HCW was found colonized with MRSA, with an antibiogram matching the outbreak strain.
Findings:
- Simultaneous implementation of multiple infection control measures was effective in curbing the outbreak.
- Screening of NICU staff and environmental cultures identified the source.
- Decolonization and redeployment of colonized HCWs were key interventions.
Implications:
- Early identification of outbreaks is critical for effective control.
- Comprehensive infection control strategies are essential in NICUs to protect neonates.
- While an epidemiological link was found, molecular confirmation of HCW transmission was not achieved in this instance.
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