Related Experiment Video
Updated: Jan 5, 2026

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
Minimally Invasive Techniques for Hirschsprung Disease
Chiara Iacusso1, Lorenzo Leonelli2, Laura Valfrè1
1Neonatal Surgery Unit, Department of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Total transanal endorectal pull-through (TEPT) and laparoscopic-assisted transanal pull-through (LA-TAPT) are effective minimally invasive surgeries for Hirschsprung disease (HD). TEPT is associated with lower patient age and weight at surgery but higher rates of perianal dermatitis.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Minimally Invasive Surgery
Background:
- Surgical treatment for Hirschsprung disease (HD) has advanced with minimally invasive techniques.
- Comparing outcomes of different minimally invasive approaches is crucial for optimizing patient care.
Purpose of the Study:
- To compare the outcomes of total transanal endorectal pull-through (TEPT) and laparoscopic-assisted transanal pull-through (LA-TAPT) for Hirschsprung disease.
- To evaluate patient demographics, postoperative complications, and hospital stay between the two surgical methods.
Main Methods:
- Retrospective analysis of patients with Hirschsprung disease undergoing TEPT or LA-TAPT between 2011 and 2016 in two Italian hospitals.
- Exclusion criteria included redo procedures, total colonic aganglionosis, and missing follow-up data.
- Comparison of patient age, weight, associated malformations, hospital stay, and early postoperative complications (within 30 days).
Main Results:
- TEPT patients were younger and lighter at surgery, with a higher incidence of congenital heart disease.
- The TEPT group experienced a longer postoperative hospital stay and a significantly higher prevalence of perianal dermatitis.
- Both groups showed similar rates of postoperative enterocolitis, redo surgery, anastomotic stenosis, and other infective complications.
Conclusions:
- Both TEPT and LA-TAPT offer surgical advantages for Hirschsprung disease.
- TEPT avoids pneumoperitoneum and transperitoneal access, but is associated with longer hospital stays and increased perianal dermatitis, likely due to younger age at operation and associated comorbidities.
Related Concept Videos
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

