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Published on: November 24, 2014
Coronary artery bypass following percutaneous transluminal coronary angioplasty
Insights
Coronary artery bypass grafting (CABG) after percutaneous transluminal coronary angioplasty (PTCA) shows a 6.3% 30-day mortality. Emergency CABG significantly increases risks of acute myocardial infarction, low cardiac output, and operative death.
Area of Science:
- Cardiology
- Cardiovascular Surgery
Background:
- Percutaneous transluminal coronary angioplasty (PTCA) is a common procedure for coronary artery disease.
- Coronary artery bypass grafting (CABG) is often performed following PTCA, especially in complex cases.
Purpose of the Study:
- To evaluate the outcomes of patients undergoing CABG after PTCA.
- To identify risk factors associated with increased mortality in this patient population.
Main Methods:
- Retrospective analysis of 286 patients who underwent CABG post-PTCA over a 4-year period.
- Comparison of outcomes between emergency and non-emergency CABG groups.
- Identification of predictors for operative death.
Main Results:
- Thirty-day mortality was 6.3% (18 patients).
- Emergency CABG (n=115) had higher rates of acute myocardial infarction (43.5% vs 4.1%), low cardiac output syndrome (34.8% vs 7.0%), and operative death (11.3% vs 2.9%) compared to non-emergency CABG.
- Previous CABG and multivessel coronary artery disease were significant predictors of operative death.
Conclusions:
- CABG following PTCA carries a significant risk, particularly in emergency settings.
- Multivessel disease and prior CABG are key risk factors for operative mortality.
- Long-term survival for early survivors is favorable at 1.4% per year.
Abstract:
During a 4-year period, 286 patients underwent coronary artery bypass grafting (CABG) following percutaneous transluminal coronary angioplasty (PTCA). Seventy-three patients had single-vessel and 213 (74.5%) had multivessel coronary artery disease. Twenty-nine patients underwent PTCA because of an evolving acute myocardial infarction (MI). Forty-two patients had previously undergone 47 CABG procedures. One hundred fifteen patients underwent CABG on an emergency basis. Indications for emergency CABG after PTCA were prolonged chest pain (79.1%), worsening of coronary artery obstruction (59.1%), "current of injury" by electrocardiogram (31.3%), cardiogenic shock (27.8%), and, in a lesser incidence, ventricular fibrillation, coronary artery dissection (without obstruction), heart block, and intractable cardiac arrest. The 286 patients underwent 2.1 CABG procedures per patient with a thirty-day mortality of 6.3% (18 patients). The incidence of acute MI was 43.5 versus 4.1%; low cardiac output syndrome, 34.8 versus 7.0%; and operative death, 11.3 versus 2.9% in the emergency and nonemergency groups, respectively. Other significant predictors of operative death were previous CABG (16.7 versus 4.5%), multivessel coronary artery disease (8.0 versus 1.4%). Late follow-up reveals a mortality of 1.4% per year in those patients who were early survivors of CABG.
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