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Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
[Study, using non-invasive methods, of prostheses manufactured at the Instituto Nacional de Cardiología Ignacio
Insights
This study evaluated bovine pericardial bioprostheses in 30 patients using echocardiography and phonocardiography. Results show acceptable functional outcomes and prosthesis performance in mitral valve replacement patients.
Area of Science:
- Cardiovascular Medicine
- Biomedical Engineering
- Cardiac Surgery
Context:
- Bovine pericardial bioprostheses are used for heart valve replacement.
- Evaluation of prosthesis performance is crucial for patient outcomes.
- Pre- and post-operative assessments guide clinical decision-making.
Purpose:
- To assess the phonocardiogram and echocardiogram characteristics of bovine pericardial bioprostheses.
- To evaluate the functional status and hemodynamic performance of these bioprostheses in patients.
- To analyze specific acoustic and hemodynamic parameters post-implantation.
Summary:
- Thirty patients received bovine pericardial bioprostheses, primarily in the mitral position.
- Phonocardiography revealed characteristic prosthesis sounds (mitral prosthesis closing click, opening click) and murmurs.
- Echocardiography demonstrated prosthesis opening velocities, E-F slope, intraventricular septum motion, and calculated valvular area.
Impact:
- Provides insights into the acoustic and hemodynamic behavior of bovine pericardial bioprostheses.
- Contributes to understanding the functional outcomes of mitral valve replacement with bioprosthetic devices.
- Supports the clinical assessment and long-term monitoring of patients with these cardiac implants.
Abstract:
We study the phonocardiogram, M mode, two-dimensional and Doppler pulsed echocardiogram of 30 patients, who underwent implantation of a bovine pericardial bioprosthesis manufactured at the Instituto Nacional de Cardiología Ignacio Chávez. We describe 26 patients with prosthesis in mitral position, 22 females and 4 males, with age between 19 to 60 years. After surgery, 22 were in functional I and 2 in class II of the New York Heart Association Criteria. Two patients (6.6%) died of extracardiac complications. Phonocardiogram: Mitral prosthesis closing click (MPCC) were recorded at all, the interval Q wave-MPCC was of 0.09 +/- 0.02 sec. The interval second sound-mitral prosthesis opening click (S2-MPOC) measured 0.10 +/- 0.01 sec. Mid-diastolic murmur were recorded in 8 patients (30.7%). The O-F slope of the apexcardiogram was of 82 +/- 40 mm/sec. Ten patients had tricuspid insufficiency. Echocardiogram: The D-E velocity of mitral prosthesis opening was of 318 +/- 99 mm/sec and the E-F slope velocity of 15 +/- 6.2 mm/sec. All patients except one showed paradoxical motion of the intraventricular septum. The prosthesis stents distance was of 14.1 +/- 2 mm, the internal diameter of 17.8 +/- 2.9 mm and the valvular area was calculated in 2.5 +/- 0.08 cm2. The flow velocity/diameter was 62.6 +/- 26.8 cm/sec/mm and the flow velocity/opening area of 52.5 +/- 26.1 cm/sec/cm2.(ABSTRACT TRUNCATED AT 250 WORDS)

