Related Experiment Video
Updated: Jan 5, 2026

02:08
Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
Published on: July 5, 2024
1.3K
PTPN2 improves implant osseointegration in T2DM via inducing the dephosphorylation of ERK
Ya-Nan Wang1,2,3, Tingting Jia1,2,3, Jiajia Zhang1,2,3
1Department of Implantology, School and Hospital of Stomatology, Shandong University, Shandong 250012, China.
Experimental Biology and Medicine (Maywood, N.J.)
|October 17, 2019
Abstract
No abstract available in PubMed .
Related Concept Videos
PI3K/mTOR/AKT Signaling Pathway
5.2K
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that regulates growth, proliferation, and cell survival in response to hormones, growth factors, or nutrient availability. This kinase exists in two structurally and functionally distinct forms: mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2). The first form (mTORC1) is composed of a rapamycin-sensitive Raptor and proline-rich Akt substrate, PRAS40. In contrast, mTORC2 consists of a...
5.2K
Transducer Mechanism: Enzyme-Linked Receptors
3.8K
Enzyme-linked receptors are cell-surface receptors acting as an enzyme or associating with an enzyme intracellularly. They make excellent drug targets. Drugs can bind to the extracellular ligand-binding domain or directly affect their enzymatic domain and alter their activity.
Major types that are helpful drug targets include:
Major types that are helpful drug targets include:
3.8K

