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Updated: Jan 5, 2026

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
Current methods for the assessment of skin microcirculation: Part 2
Jolanta Neubauer-Geryk1, Magdalena Hoffmann2, Melanie Wielicka3
1Clinical Physiology Unit, Medical Simulation Centre, Medical University of Gdansk, Gdansk, Poland.
This study reviews non-invasive methods for assessing skin microcirculation, focusing on techniques applicable to clinical research. Understanding skin microcirculation is vital for diagnosing various systemic and dermatological conditions.
Area of Science:
- Cardiovascular Physiology
- Dermatology
- Vascular Biology
Background:
- Microcirculation constitutes 99% of adult blood vessels, bridging arterial and venous systems.
- Skin microcirculation involves superficial and deep vascular plexuses, including small arteries, veins, lymphatics, and anastomoses.
- Disruptions in skin microcirculation are linked to systemic diseases and specific skin disorders.
Purpose of the Study:
- To detail non-invasive methods for evaluating skin microcirculation.
- To focus on techniques suitable for clinical research settings.
- To complement previous reviews on clinical practice methods.
Main Methods:
- Review of non-invasive assessment techniques for skin microcirculation.
- Focus on methods applicable in clinical research.
- Exclusion of methods primarily used in routine clinical practice.
Main Results:
- The article provides a comprehensive overview of research-oriented non-invasive techniques.
- It highlights the importance of these methods for understanding skin pathophysiology.
- The review categorizes techniques based on their application in research.
Conclusions:
- Various non-invasive methods are available for studying skin microcirculation in research.
- These techniques are crucial for advancing the understanding of skin health and disease.
- The article serves as a resource for researchers investigating microcirculatory functions in the skin.
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