Chronobiologic pattern discrimination of plasma hormones, notably DHEA-S and TSH, classifies an expansive personality

Methods of chronobiologic pattern discrimination, a "monotest' involving the leave-one-out technique and a "maximin distance' algorithm for cluster analysis, along with stepwise discriminant analysis procedures and correlation techniques are used in the search for classifiers of personality. By these methods, chronoendocrine relations of an expansive personality are explored in data sampled around the clock in 4 seasons on 10 North American and 3 Japanese women. Of 12 plasma hormones determined in each season, DHEA-S shows a time-dependent relation to an expansive, egocentric personality assessed by an abbreviated version of the Minnesota Multiphasic Personality Inventory; time-dependent co-classifiers are TSH, LH, prolactin and cortisol. Cost-effective recommendations for sampling are thus proposed for further tests of endocrine factors classifying for an expansive personality and, perhaps, classifying also for any associated vulnerability or risk state.