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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
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Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
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Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
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Thyroid hormone misuse and abuse.

Victor J Bernet1,2

  • 1Division of Endocrinology, Mayo Clinic, Mayo Clinic School of Medicine, Jacksonville, FL, 32224, USA. bernet.victor@mayo.edu.

Endocrine
|October 17, 2019
PubMed
Summary
This summary is machine-generated.

Thyroid hormone (TH) misuse, whether intentional for weight loss or unintentional through supplements, poses health risks. Understanding these risks is crucial for public safety and proper medical guidance.

Keywords:
AnalogsFactitious thyrotoxicosisOverdoseSupplementsThyroid hormone abuseThyroid hormone misuseThyrotoxicosis

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Area of Science:

  • Endocrinology
  • Public Health

Background:

  • Thyroid hormone (TH) is vital for human physiology.
  • Maintaining optimal TH levels is critical for overall health.
  • TH misuse and abuse can lead to significant health risks.

Purpose of the Study:

  • To highlight the risks associated with thyroid hormone misuse and abuse.
  • To inform the public and healthcare providers about unapproved uses of TH.
  • To address both intentional and unintentional exposures to exogenous TH.

Main Methods:

  • Review of existing literature on thyroid hormone misuse.
  • Analysis of reported cases of intentional and unintentional TH exposure.
  • Examination of medical guidelines and controversies surrounding TH prescription.

Main Results:

  • Intentional misuse includes using TH for weight loss or energy enhancement.
  • Healthcare providers may prescribe TH for outdated or controversial indications.
  • Unintentional exposure can occur through contaminated supplements or food.

Conclusions:

  • Exposure to exogenous thyroid hormone, regardless of the source, carries potential adverse side effects.
  • Public awareness and education are essential to prevent TH misuse.
  • Prudent medical practice is necessary to avoid inappropriate TH prescriptions.