Related Experiment Video

Updated: Jan 5, 2026

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling
10:49

Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling

Published on: September 20, 2016

13.2K

A Photoactivatable Small-Molecule Probe for the In Vivo Capture of Polyketide Intermediates

Samantha L Kilgour1, Robert Jenkins1, Manuela Tosin1

  • 1Department of Chemistry, University of Warwick, Library Road, Coventry, CV4 7AL, UK.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|October 17, 2019
PubMed

Keywords:
bioorganic chemistrybiosynthesisintermediate capturephotoactivatable probespolyketides

More Related Videos

In Vivo Proximity Biotinylation for Protein Interaction Studies in Paramecium tetraurelia06:43

In Vivo Proximity Biotinylation for Protein Interaction Studies in Paramecium tetraurelia

Published on: September 12, 2025

1.0K
In Vivo Application of TurboID-based Proximity Labeling in Drosophila melanogaster09:59

In Vivo Application of TurboID-based Proximity Labeling in Drosophila melanogaster

Published on: June 13, 2025

1.1K

Related Concept Videos

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
9.2K
In-situ Hybridization02:31

In-situ Hybridization

In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...
10.4K