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Pediatric enteral nutrition therapy for burn victims: when should it be initiated?

Mariéle Valentini1, Fernanda Braga Seganfredo2, Sabrina Alves Fernandes3

  • 1Hospital de Pronto Socorro de Porto Alegre - Porto Alegre (RS), Brasil.

Revista Brasileira De Terapia Intensiva
|October 17, 2019
PubMed

Insights

Early enteral nutrition in pediatric burn patients significantly reduces hospital stays. While not impacting mortality, it improves metabolic markers and reduces caloric deficits, though with increased gastrointestinal side effects.

Area of Science:

  • Pediatric critical care
  • Nutritional science
  • Burn management

Background:

  • Early nutritional intervention is crucial for pediatric burn patients.
  • Optimizing enteral nutrition timing may improve outcomes.
  • Evidence on early versus late enteral nutrition initiation is limited.

Purpose of the Study:

  • To systematically review and meta-analyze evidence on early enteral nutrition (EEN) initiation in pediatric burn patients.
  • To compare outcomes of EEN versus late enteral nutrition (LEN).

Main Methods:

  • Systematic review and meta-analysis of randomized clinical trials.
  • Searched MEDLINE/PubMed, Embase, and Cochrane Library.
  • Included pediatric patients (1 month to 18 years) with burns.

Main Results:

  • No significant difference in mortality between EEN and LEN groups (OR = 0.72).
  • EEN significantly reduced length of hospital stay by 3.69 days (p < 0.00001).
  • EEN group showed increased diarrhea/vomiting, decreased intestinal permeability, higher insulin levels, and lower caloric deficit/weight loss.

Conclusions:

  • Initiating nutritional support early is important for pediatric burn patients.
  • EEN demonstrates metabolic benefits and shorter hospitalizations.
  • Further robust studies are needed to enhance scientific impact.
Abstract

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