Effect of short-term, high-intensity exercise training on human skeletal muscle citrate synthase maximal activity:
Martin J MacInnis1,2, Lauren E Skelly1, F Elizabeth Godkin1
1Department of Kinesiology, McMaster University, Hamilton, ON L8S 4K1, Canada.
Abstract:
The legs of 9 men (age 21 ± 2 years, 45 ± 4 mL/(kg·min)) were randomly assigned to complete 6 sessions of high-intensity exercise training, involving either one or four 5-min bouts of counterweighted, single-leg cycling. Needle biopsies from vastus lateralis revealed that citrate synthase maximal activity increased after training in the 4-bout group (p = 0.035) but not the 1-bout group (p = 0.10), with a significant difference between groups post-training (13%, p = 0.021). Novelty Short-term training using brief intense exercise requires multiple bouts per session to increase mitochondrial content in human skeletal muscle.
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