Risk Factors of Transient Cortical Blindness After Cerebral Angiography: A Multicenter Study

Miao Li1, Huaxin Liang1, Chao Liu2

  • 1Department of Neurosurgery, The China-Japan Union Hospital of Jilin University, Changchun, China.

Frontiers in Neurology
|October 18, 2019
PubMed

Insights

Transient cortical blindness after cerebral angiography is rare but linked to higher contrast agent doses and posterior circulation injections. Identifying these risk factors is crucial for patient safety.

Area of Science:

  • Neurology
  • Radiology
  • Ophthalmology

Background:

  • Transient cortical blindness is a rare but significant complication following cerebral angiography.
  • Identifying risk factors for this complication is clinically important for patient management and safety.

Purpose of the Study:

  • To identify independent predictive factors for transient cortical blindness after cerebral angiography.

Main Methods:

  • A multicenter cohort study involving 5,126 patients who underwent cerebral angiography.
  • Analysis of patient baseline characteristics and procedure-related factors using multivariate logistic regression.

Main Results:

  • Eighteen patients (0.35%) experienced transient cortical blindness.
  • Higher contrast agent dose and injection into the posterior circulation were identified as independent predictive factors (P < 0.05).
  • No significant differences were found regarding gender, age, smoking, diabetes, or hypertension.

Conclusions:

  • Increased contrast agent dose and posterior circulation contrast injection are potential independent risk factors for transient cortical blindness post-cerebral angiography.
  • These findings can inform strategies to mitigate the risk of this complication.