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Updated: Aug 10, 2026
Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Treatment of diffuse transitional cell carcinoma in situ by whole bladder hematoporphyrin derivative photodynamic
Abstract:
A total of 10 patients with diffuse, resistant transitional cell carcinoma of the bladder underwent whole bladder hematoporphyrin derivative photodynamic therapy in which a new light bulb fiber was used to deliver red light (630 nm.) from an argon pumped dye laser. Six patients who had carcinoma in situ alone had a complete response, 2 with diffuse carcinoma in situ and stage Ta lesions had persistent stage Ta disease and 2 with diffuse carcinoma in situ and focal stage T2 disease had disappearance of the carcinoma in situ but persistent invasive disease at 3 months. This new light delivery system appears to be effective in the treatment of diffuse, resistant carcinoma in situ of the bladder.
