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The influence of device handles in single-molecule experiments
Luca Bellino1, Giuseppe Florio2, Giuseppe Puglisi3
1Politecnico di Bari, (DMMM) Dipartimento di Meccanica, Matematica e Management, Politecnico di Bari, Via Re David 200, 70125, Italy. luca.bellino@poliba.it giuseppe.florio@poliba.it.
Soft Matter
|October 18, 2019
Abstract:
We deduce a fully analytical model to predict the artifacts of the device handles in single molecule force spectroscopy experiments. As we show, neglecting the handle stiffness can lead to crucial overestimation or underestimation of the stability properties and unfolding thresholds of multistable molecules.
