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Updated: Jan 5, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
Published on: September 22, 2023
[Research progress on the role of IL-33/ST2 axis in pathogenesis of allergic rhinitis]
Abstract:
SummaryThe binding of IL-33 and its receptor ST2 plays a key role in the development of cardiovascular diseases, chronic inflammation, allergic diseases and fibrosis related diseases. The study of the relationship between IL-33/ST2 signaling pathway and these diseases may provide new ideas and methods for the diagnosis and treatment of diseases. Although many high-quality studies have been done on the role of IL-33/ST2 signaling pathway in the pathogenesis of allergic rhinitis, there is still a lack of comprehensive and clear explanation. This paper reviews the role of IL-33/ST2 signaling pathway in the pathogenesis of allergic rhinitis on the basis of literature review. This signaling pathway can be used to guide the treatment of allergic rhinitis in theory.
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