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Direct Pulp Capping: Which is the Most Effective Biomaterial? A Retrospective Clinical Study
Anabela Paula1, Eunice Carrilho2, Mafalda Laranjo3
1Institute of Integrated Clinical Practice, Institute for Clinical and Biomedical Research (iCBR), Centre for Innovative Biomedicine and Biotechnology (CIBB), Area of Environment Genetics and Oncobiology (CIMAGO), CNC.IBILI, Faculty of Medicine, University of Coimbra, 3000-075 Coimbra, Portugal. anabelabppaula@sapo.pt.
Biodentine™ and mineral trioxide aggregate (MTA) show similar high success rates for direct pulp capping in humans. Both biomaterials effectively promote dentin bridge formation with minimal inflammation, proving safe and effective.
Area of Science:
- Dentistry
- Biomaterials Science
- Regenerative Medicine
Background:
- Tricalcium silicate cements, like Biodentine™, offer improved handling properties over traditional mineral trioxide aggregate (MTA) cements.
- Biodentine™ contains a calcium hydroxide base and shares desirable characteristics with MTA, making it a promising alternative in dental applications.
Purpose of the Study:
- To compare the clinical efficacy and outcomes of Biodentine™ versus WhiteProRoot® MTA in direct pulp capping procedures.
- To evaluate the formation of dentin bridges, pulp inflammation, and periapical tissue health following direct pulp capping with these biomaterials.
Main Methods:
- A retrospective clinical study involving 20 patients undergoing direct pulp capping.
- Clinical assessment of pulp inflammation symptoms, radiographic evaluation of periapical tissues, and analysis of restorative alterations.
- Comparison of Biodentine™ and WhiteProRoot® MTA treatments.
Main Results:
- Both biomaterials demonstrated high success rates at 6 months: 100% for MTA and 95% for Biodentine™.
- No statistically significant differences were observed between Biodentine™ and MTA in terms of success rates.
- Clinical success was independent of operating field isolation, exposure size, etiology, or restorative material type.
Conclusions:
- Biodentine™ exhibits a therapeutic effect, promoting dentin bridge formation with minimal inflammatory signs.
- Biodentine™ shows a high clinical success rate, comparable to MTA, for direct pulp capping in humans.
- The findings support the safe and effective use of Biodentine™ as a direct pulp capping agent.
