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Heterochromatic variants and their association with neoplasias: V. Non-Hodgkin's lymphomas
M Labal de Vinuesa1, I Slavutsky, M Mudry de Pargament
1Centro Austral de Investigaciones Científicas (CADIC), Tierra del Fuego, Argentina.
Cancer Genetics and Cytogenetics
|April 1, 1988
Abstract:
A study of heterochromatic regions in chromosomes #1, #9, and #16 was performed on lymphocytes of peripheral blood from 55 normal individuals and 50 patients with non-Hodgkin's lymphoma (NHL). Heteromorphism was present in 90% of the NHL patients, compared with 44% in normal individuals (p less than 0.001). An increase of inv(1), 1qh-, and 9qh-variants was observed in malignant lymphoma patients with respect to controls.