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A TCR-Dependent Tissue Repair Potential of MAIT Cells
1INSERM U932, PSL University, Institut Curie, Paris 75005, France.
Abstract:
Three studies published in Cell Reports (Hinks et al., Lamichhane et al., and Leng et al.) describe the transcriptome of human and mouse mucosal-associated invariant T (MAIT) cells after cognate and noncognate stimulation. The results confirm the variability of MAIT cell effector functions and provide evidence of a new tissue-repair gene signature expressed upon T cell receptor (TCR) stimulation.
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