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Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

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Published on: April 28, 2015

Multimodal Composite Iron Oxide Nanoparticles for Biomedical Applications.

Shameer Pillarisetti¹, Saji Uthaman², Kang Moo Huh²

¹1Department of Biomedical Science, BK21 PLUS Center for Creative Biomedical Scientists, Chonnam National University Medical School, 42 Jebong-ro, Dong-gu, Gwangju, 61469 Republic of Korea.

Tissue Engineering and Regenerative Medicine

|October 19, 2019

Summary

Composite iron oxide nanoparticles (CIONPs) offer advanced multimodal imaging and therapeutic applications. Further research into their long-term in vivo effects will unlock their full potential for treating various medical diseases.

Keywords:

Iron oxide nanoparticles Magnetic resonance imaging Optical imaging Photoacoustic imaging Ultrasound imaging

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Synthesis of 68Ga Core-doped Iron Oxide Nanoparticles for Dual Positron Emission Tomography /T1Magnetic Resonance Imaging

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Published on: November 20, 2018

Area of Science:

Nanotechnology
Biomedical Engineering
Materials Science

Background:

Iron oxide nanoparticles (IONPs) exhibit superior colloidal stability and in vivo biocompatibility, making them ideal for biomedical imaging.
Material scientists have optimized IONPs' imaging and optical properties through modifications in size, shape, phase, and surface characteristics.
Combining IONPs with other imaging modalities has led to high-resolution imaging platforms, with composite IONPs (CIONPs) showing promise for therapeutic applications.

Purpose of the Study:

To review recent advancements in CIONPs for multimodal imaging.
To focus on the therapeutic applications of CIONPs.

Main Methods:

Review of literature on composite iron oxide nanoparticles (CIONPs).
Focus on CIONPs for multimodal imaging and therapeutic applications.

Main Results:

CIONPs are utilized for theranostic applications, including imaging-guided photothermal therapy.
IONP-based nanoparticles demonstrate potential in phototherapeutics.

Conclusions:

CIONP-based nanoparticles are effective for theranostic applications.
Further investigation into the long-term in vivo effects of CIONPs is necessary.
Addressing these long-term effects will enable broader applications of multifunctional CIONPs in treating diverse medical diseases.