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Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
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Type I neurofibromatosis with spindle cell sarcoma: A case report
Yu Zhang1, Jiao-Jiao Chao1, Xiu-Feng Liu2
1BaYi Hospital Affiliated to Nanjing University of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing 210000, Jiangsu Province, China.
World Journal of Clinical Cases
|October 19, 2019
Summary
Neurofibromatosis type I (NF1) is a common genetic disorder. This case highlights NF1 with spindle cell sarcoma, emphasizing the potential of targeted therapy alongside traditional treatments.
Area of Science:
- Oncology
- Genetics
- Dermatology
Background:
- Neurofibromatosis type I (NF1) is the most common neurofibromatosis subtype.
- NF1 is associated with tumor-suppressor syndromes and a high incidence of tumors.
- Reports on NF1 with spindle cell sarcoma are rare.

