Metal nanoparticles synthesis through natural phenolic acids

Area of Science:

• Green chemistry and nanotechnology
• Materials science and engineering
• Biomedical applications of nanomaterials

Background:

• Nanostructures require biocompatibility and eco-friendliness for therapeutic use.
• Plant-derived phenolic acids are effective natural agents for nanoparticle synthesis.
• Phenolic acids act as both reducing agents and stabilizers in nanoparticle production.

Purpose of the Study:

• To review phenolic acid-mediated synthesis of metallic and metallic oxide nanoparticles (NPs).
• To explore the biomedical applications of these synthesized NPs.
• To discuss the mechanisms, characterization, and toxicity of phenolic acid-derived NPs.

Main Methods:

• Green synthesis utilizing plant-derived phenolic acids.
• Investigating the roles of phenolic acids as reducing agents and stabilizers.
• Characterization and toxicity assessment of synthesized metal NPs.

Main Results:

• Phenolic acids provide a reproducible, simple, profitable, and cost-effective strategy for NP synthesis.
• Phenolic acids, as antioxidants, offer health benefits.
• The review covers mechanisms of bioreduction, surface adsorption, characterization, and toxicity.

Conclusions:

• Phenolic acid-mediated synthesis is a viable green route for producing biocompatible NPs.
• These NPs hold significant potential for various biomedical applications.
• Further research is needed to fully understand and optimize their use.