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Area of Science:

  • Pediatric Medicine
  • Genetics
  • Respiratory Medicine

Background:

  • VACTERL association is a complex congenital disorder characterized by vertebral anomalies, anal atresia, cardiac defects, tracheoesophageal fistula/esophageal atresia, renal anomalies, and limb defects.
  • Airway abnormalities are infrequently reported in VACTERL association, making their recognition vital.

Observation:

  • A 10-month-old infant with a history of anal atresia presented with recurrent cough and fever.
  • The patient was diagnosed with VACTERL association.

Findings:

  • Diagnostic imaging, including bronchoscopy and chest CT with computed tomography angiography, revealed multiple airway abnormalities.
  • Specific findings included a bridging bronchus, airway malacia, and complete tracheal rings.

Implications:

  • This case highlights that multiple airway anomalies can be associated with VACTERL association.
  • Comprehensive evaluation of the tracheobronchial system using advanced imaging and bronchoscopy is recommended for patients with VACTERL association, particularly those with respiratory symptoms.