Related Experiment Video
Updated: Jan 5, 2026

04:04
Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
10.9K
[Segmentectomy in patients with primary pulmonary malignancies].
A M Amiraliev1, O V Pikin1, A B Ryabov1
1Herzen Moscow Oncology Research Institute - Branch of the National Medical Radiology Research Center, Moscow, Russia.
Khirurgiia
|October 19, 2019
Summary
Segmentectomy and lobectomy show comparable outcomes for early-stage non-small cell lung cancer (NSCLC). Segmentectomy is a suitable option for patients with reduced lung function or significant comorbidities, offering similar survival rates.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Pulmonary Medicine
Background:
- Early-stage non-small cell lung cancer (NSCLC) management involves surgical resection.
- Anatomical segmentectomy and lobectomy are primary surgical approaches.
- Comparing outcomes of these procedures is crucial for treatment optimization.
Purpose of the Study:
- To compare the immediate and long-term results of anatomical segmentectomy versus lobectomy for peripheral NSCLC stage IA1-2.
- To evaluate mortality, morbidity, and 5-year survival rates between the two surgical techniques.
Main Methods:
- Retrospective analysis of 200 patients with peripheral NSCLC (cT1a-bN0M0, tumor ≤2 cm).
- Patients underwent either lobectomy (n=148) or segmentectomy (n=52).
- Propensity score matching created comparable groups (46 pairs) for analysis of outcomes.
Main Results:
- No mortality was observed in either group.
- Similar morbidity rates were reported for segmentectomy (8.69%) and lobectomy (6.52%).
- Five-year survival rates were comparable: 82% for segmentectomy and 86% for lobectomy.
Conclusions:
- Segmentectomy and lobectomy yield comparable postoperative results and long-term outcomes in patients with early-stage NSCLC.
- Segmentectomy is a recommended surgical option for patients with limited pulmonary function or severe comorbidities.

