Liver MR Elastography Technique and Image Interpretation: Pearls and Pitfalls
Flavius F Guglielmo1, Sudhakar K Venkatesh1, Donald G Mitchell1
1From the Department of Radiology, Thomas Jefferson University Hospital, 132 S 10th St, Philadelphia, PA 19107 (F.F.G., D.G.M.); and Department of Radiology, Mayo Clinic, Rochester, Minn (S.K.V.).
Summary
Accurate liver stiffness measurement using MR elastography requires optimizing imaging technique, performing prompt quality control, and proper interpretation. This ensures reliable assessment of liver fibrosis and cirrhosis stages.
Area of Science:
- Medical Imaging
- Hepatology
- Radiology
Background:
- Liver MR elastography measures liver stiffness to evaluate fibrosis and cirrhosis.
- Accurate liver stiffness measurement (LSM) is crucial for staging liver fibrosis.
Purpose of the Study:
- To review the core components of liver MR elastography for accurate and reliable LSM.
- To provide guidance on optimizing imaging technique, quality control, and interpretation for clinical services.
Main Methods:
- Optimization of six technical parameters: patient fasting, driver placement, section positioning, end-expiration sequencing, timing, and pulse sequence parameters.
- Immediate review of elastograms for diagnostic quality and potential repeat scans.
- Understanding proper LSM technique, including measurement areas and confounding factors.
Main Results:
- Detailed review of technical parameter optimization for MR elastography.
- Emphasis on prompt quality control and immediate assessment of elastogram quality.
- Guidance on accurate interpretation and reporting of elastography findings, considering various causes of increased liver stiffness.
Conclusions:
- Mastery of imaging technique, quality control, and interpretation is essential for reliable liver MR elastography.
- This review provides a framework for implementing and operating a clinical liver MR elastography service.
- Properly performed and interpreted MR elastography aids in the evaluation of liver fibrosis and cirrhosis.
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