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Updated: Jan 5, 2026

Cortisol Measurement in Koala Phascolarctos cinereus Fur
Published on: August 23, 2019
PiRNAs Rise to Rescue Koalas
Astrid D Haase1, Todd S Macfarlan2
1National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Abstract:
PIWI-interacting small RNAs (piRNAs) establish sequence-specific adaptive restriction of resident genomic parasites to guard genome integrity. In this issue of Cell, Yu, Koppetsch, et al. describe an innate piRNA-response that specifically fragments the viral RNA genome in the germline of recently invaded koalas. This first line of defense might ensure survival until adaptive immunity develops.
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