Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Separation of Sister Chromatids

Separation of Sister Chromatids

At the transition from prophase to metaphase, there is a reduction in cohesion along the chromosomal arms, resulting in the resolution of sister chromatids. However, residual cohesin connections remain to hold the sister chromatids together until the transition from metaphase to anaphase. The residual connection prevents any premature separation of sister chromatids, blocking the risks of aneuploidy within the daughter cells.
At the onset of anaphase, separase, a proteolytic enzyme, is...

The Spindle Assembly Checkpoint

The Spindle Assembly Checkpoint

The spindle assembly checkpoint is a molecular surveillance mechanism ensuring the fidelity of chromosome segregation during anaphase. The checkpoint monitors the completion of all the prerequisite steps before chromosome segregation to determine whether the segregation process should proceed or be delayed.
Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular maps of diseases from omics data and network embeddings.

NPJ systems biology and applications·2026

Same author

CCMRI: a classification and curated database of climate change-related microbiome studies.

Scientific reports·2026

Same author

LLM-Assessed Relatedness of Microbiome Study Descriptions Aligns more Strongly with Functional than with Taxonomic Profile Similarity.

Microbial ecology·2026

Same author

Accurate plasmid reconstruction from metagenomics data using assembly-alignment graphs and contrastive learning.

Nature biotechnology·2026

Same author

Single-cell atlas of transcriptomic vulnerability across multiple neurodegenerative and neuropsychiatric diseases.

medRxiv : the preprint server for health sciences·2026

Same author

Cross-disease analysis identifies the inflammatome as a transcriptional program of inflammation.

Cell reports·2026

Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026

Same journal

Systematic discovery of pathogen effector functions across human pathogens and pathways.

Cell·2026

Same journal

Structural basis for host membrane binding and remodeling by invading malaria parasites.

Cell·2026

Same journal

Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning.

Cell·2026

Same journal

Arc mediates intercellular tau transmission via extracellular vesicles.

Cell·2026

Same journal

Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression.

Cell·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 5, 2026

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Published on: February 20, 2017

SnapShot: S-Phase Entry and Exit.

Andrew Burgess¹, Jenny Vuong², Kamila A Marzec¹

¹ANZAC Research Institute, University of Sydney, Sydney NSW 2139, Australia.

|October 19, 2019

Summary

This summary is machine-generated.

This study visualizes over 80 key events regulating cell cycle S-phase entry and exit. The new S-phase visualization complements an existing M-phase one for a complete cell division overview.

More Related Videos

Determination of S-Phase Duration Using 5-Ethynyl-2'-deoxyuridine Incorporation in Saccharomyces cerevisiae

Determination of S-Phase Duration Using 5-Ethynyl-2'-deoxyuridine Incorporation in Saccharomyces cerevisiae

Published on: October 21, 2022

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Published on: May 27, 2021

Related Experiment Videos

Last Updated: Jan 5, 2026

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Published on: February 20, 2017

Determination of S-Phase Duration Using 5-Ethynyl-2'-deoxyuridine Incorporation in Saccharomyces cerevisiae

Determination of S-Phase Duration Using 5-Ethynyl-2'-deoxyuridine Incorporation in Saccharomyces cerevisiae

Published on: October 21, 2022

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Neutron Spin Echo Spectroscopy as a Unique Probe for Lipid Membrane Dynamics and Membrane-Protein Interactions

Published on: May 27, 2021

Area of Science:

Cell Biology
Molecular Biology
Biochemistry

Background:

Cell cycle progression relies on precise timing of protein complex assembly.
Understanding the regulation of S-phase (synthesis phase) is crucial for cell division.

Purpose of the Study:

To create a comprehensive visualization of S-phase regulation.
To integrate S-phase events with existing M-phase visualizations for a holistic cell cycle view.

Main Methods:

Developed a tailored visualization using the Minardo layout.
Highlighted over 80 essential S-phase regulatory events.

Main Results:

A detailed visualization of S-phase entry and exit regulation is now available.
The S-phase visualization complements the previously developed M-phase visualization.

Conclusions:

The combined visualizations offer a comprehensive overview of cell division cycle regulation.
This resource aids in understanding the interplay of events governing cell division.