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Updated: Jan 5, 2026

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
Published on: October 2, 2019
Sleep disorders in low-risk preschool very preterm children
Domenico M Romeo1, Giuseppina Leo1, Leonardo Lapenta1
1Pediatric Neurology Unit, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Insights
Preschool-aged very preterm children have a slightly increased risk of sleep disorders compared to term-born peers. Specific issues include breathing problems and difficulty initiating sleep, warranting clinical screening.
Area of Science:
- Pediatric Sleep Medicine
- Neonatal Follow-up
- Developmental Pediatrics
Background:
- Preterm birth is associated with various developmental challenges.
- Sleep disturbances can impact neurodevelopment and overall health in children.
- Assessing sleep in very preterm children without neurological disabilities is crucial for early intervention.
Purpose of the Study:
- To evaluate sleep disorders in preschool-aged very preterm children (gestational age ≤ 31 weeks).
- To compare sleep patterns between very preterm children and a control group of term-born children.
- To identify specific sleep issues prevalent in the preterm population.
Main Methods:
- 146 low-risk very preterm children (mean GA 28 weeks) and 146 term-born controls were assessed at preschool age (mean 3.8 years).
- The Sleep Disturbance Scale for Children (SDSC) was used to evaluate sleep problems in both groups.
- Children had no history of neurological disabilities.
Main Results:
- 7% of preterm children had abnormal total sleep scores, and 21% had abnormal scores on at least one SDSC factor.
- The preterm group reported significantly higher median scores for total sleep, sleep-disordered breathing, sleep hyperhidrosis, and sleep-initiation/maintenance difficulties.
- No significant differences were found based on age at assessment or gestational age.
Conclusions:
- Very preterm children exhibit a slightly higher incidence of sleep disorders compared to term-born peers.
- Specific sleep factors like breathing and initiation difficulties are more common in preterm children.
- Findings support clinical screening for sleep disorders in at-risk preterm children for timely diagnosis and treatment.
Objectives:
(i) to assess the presence of sleep disorders in a population of very preterm children (ie, with a gestational age [GA] ≤ 31 weeks) of preschool age with no history of neurological disabilities using a questionnaire standardized for this age group and (ii) to identify possible differences in a control group of term-born children.
Methods:
A total of 146 low-risk preterm children (mean gestational age 28 weeks; range: 25-30), were assessed at a preschool age (mean age 3.8 years; range 3-6 years) using the sleep disturbance scale for children (SDSC) to assess sleep problems. As controls, 146 typically developing children matched for age and gender were also evaluated using the SDSC.
Results:
An abnormal total sleep score (>70) was found in 7% of preterm children, while 21% had an abnormal score on at least one SDSC factor. No significant differences were reported according to the age of assessment or gestational age. The preterm group reported higher significant median scores on SDSC total, sleep-disordered breathing, sleep hyperhidrosis and difficulty in initiating and maintaining sleep factors.
Conclusions:
Low-risk very preterm children showed only a slightly higher incidence of sleep disorders than term-born peers at preschool age, with higher scores in specific sleep factors. These data could be useful to clinicians for screening those preterm children at risk for sleep disorders who need a more detailed assessment for a conclusive diagnosis and treatment.
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