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Quantifying hemodynamics within an aneurysm exposed to prolonged exercise levels
Mehul Varshney1, M Haani Farooqi2, Abdullah Y Usmani1
1Department of Mechanical Engineering, ZHCET, AMU, Aligarh 202002 India.
Computer Methods and Programs in Biomedicine
|October 19, 2019
Summary
Mild exercise may offer an optimal non-invasive treatment for abdominal aortic aneurysms by reducing particle residence time. However, moderate exercise increases wall pressure, suggesting a balance is needed for effective treatment.
Area of Science:
- Cardiovascular biomechanics
- Medical fluid dynamics
- Aneurysm research
Background:
- Abdominal aortic aneurysms (AAAs) require non-invasive treatment strategies.
- Understanding blood flow dynamics within aneurysms under varying physiological conditions is crucial.
Purpose of the Study:
- To explore blood flow patterns and hemodynamic indicators in a 2-D aneurysm model.
- To quantify the impact of resting, mild, and moderate exercise on flow dynamics.
- To determine an optimal exercise level for attenuating AAA disease progression.
Main Methods:
- Numerical simulations using the finite volume method (ANSYS-Fluent).
- Analysis of flow topology, vorticity, and hemodynamic indicators (TAWSS, OSI).
- Utilized Discrete Phase Material (DPM) to visualize particle deposition and Particle Residence Index (PRI).
Main Results:
- Vortex impingement causes pressure peaks within the aneurysm.
- Exercise significantly increases the maximum TAWSS (wall shear stress) along the flow separation zone.
- Moderate exercise distributes oscillatory loading (OSI) across the aneurysm wall, reducing particle clearance time (PRI).
Conclusions:
- Resting conditions lead to prolonged fluid recirculation against the aneurysmal wall.
- Mild exercise demonstrates potential for non-invasive AAA treatment by balancing particle clearance and wall stress.
- Moderate exercise, while efficient for particle clearance, poses risks due to high pressure on the aneurysm wall.

