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Altered neurodevelopmental trajectories of brain structure in Tourette syndrome and Chronic Tic Disorders.

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Related Experiment Video

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Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
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[Patients with tic disorders: widely known, yet underserved].

Jaana M L Schnell, Elif Weidinger, Richard Musil

    Fortschritte Der Neurologie-Psychiatrie
    |October 19, 2019
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    Summary

    Tic disorders, including Tourette syndrome, involve involuntary motor and vocal tics. Management focuses on diagnosis, psychoeducation, behavioral therapies, and treating psychiatric comorbidities.

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    Area of Science:

    • Neurology
    • Psychiatry
    • Genetics

    Background:

    • Tic disorders, such as Tourette syndrome, manifest in childhood with motor and vocal tics, often fluctuating in severity.
    • These disorders are frequently associated with psychiatric comorbidities like ADHD and anxiety.
    • The underlying cause involves complex genetic and environmental factors affecting brain networks.

    Purpose of the Study:

    • To provide an overview of tic disorders, their classification, and associated conditions.
    • To discuss diagnostic approaches and the importance of psychoeducation.
    • To review current and emerging therapeutic strategies for tic disorders.

    Main Methods:

    • Literature review of tic disorder classification, etiology, and treatments.
    • Analysis of diagnostic criteria and psychoeducational approaches.
    • Evaluation of psychotherapeutic and psychopharmacological interventions.

    Main Results:

    • Tic disorders are categorized into provisional and chronic types, with Tourette syndrome being a prominent example.
    • Effective management requires accurate diagnosis, psychoeducation, and treatment of comorbidities.
    • Therapeutic options include behavioral interventions (e.g., HRT, ERP) and medications (e.g., aripiprazole, risperidone).

    Conclusions:

    • Comprehensive management of tic disorders involves addressing both tics and co-occurring psychiatric conditions.
    • Behavioral therapies and pharmacotherapy are key components of treatment.
    • Further research into novel treatments like cannabinoids is warranted.