Related Experiment Video
Updated: Jan 5, 2026

Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter
Published on: March 31, 2022
[Edge-to-edge repair : What has changed compared to the position paper in 2013?]
1Klinik für Kardiologie und Angiologie, Herzentrum Siegburg, Ringstr. 49, 53721, Siegburg, Deutschland. Peter.Boekstegers@helios-gesundheit.de.
This review discusses updated interventional strategies for secondary mitral valve regurgitation using edge-to-edge repair. It compares current European Society of Cardiology guidelines and technical advancements since 2013.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Secondary mitral valve regurgitation (SMVR) management has evolved significantly.
- Previous guidelines from 2013 require updated comparison with current practices.
- Edge-to-edge repair is a key interventional technique for SMVR.
Purpose of the Study:
- To review and compare current interventional treatment strategies for SMVR with edge-to-edge repair.
- To analyze changes since the 2013 German position paper.
- To incorporate 2017 European Society of Cardiology (ESC) guidelines and recent technical developments.
Main Methods:
- Literature review of current data and guidelines.
- Comparative analysis of interventional strategies.
- Discussion of intraprocedural assessment techniques for mitral regurgitation.
Main Results:
- Significant advancements in edge-to-edge repair techniques for SMVR.
- Updated recommendations based on 2017 ESC guidelines.
- Improved intraprocedural assessment methods enhance repair outcomes.
Conclusions:
- Interventional edge-to-edge repair is a refined strategy for SMVR.
- Current guidelines and technology offer improved treatment options.
- Continuous evaluation of data and techniques is crucial for optimal patient care.
More Related Videos
13:06Visualization of miniSOG Tagged DNA Repair Proteins in Combination with Electron Spectroscopic Imaging ESI
Published on: September 24, 2015
11:58A Simple, Rapid, and Quantitative Assay to Measure Repair of DNA-protein Crosslinks on Plasmids Transfected into Mammalian Cells
Published on: March 5, 2018
Related Concept Videos
Long-patch Base Excision Repair
Fixing Double-strand Breaks
Fixing Double-strand Breaks
Overview of DNA Repair
Chemically...
Overview of DNA Repair
Mismatch Repair