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Updated: Jan 5, 2026

Using Next Generation Sequencing to Identify Mutations Associated with Repair of a CAS9-induced Double Strand Break Near the CD4 Promoter
Published on: March 31, 2022
[Edge-to-edge repair : What has changed compared to the position paper in 2013?]
1Klinik für Kardiologie und Angiologie, Herzentrum Siegburg, Ringstr. 49, 53721, Siegburg, Deutschland. Peter.Boekstegers@helios-gesundheit.de.
Abstract:
This short review article aims to explain the changes in the treatment strategies of interventional care designed to treat secondary mitral valve regurgitation with edge-to-edge repair in comparison to the position paper published in 2013 by the German Society of Cardiology and the German Society of Thoracic and Cardiovascular Surgery. To this end the current data situation with respect to the European Society of Cardiology (ESC) guidelines from 2017, the intraprocedural assessment of mitral valve regurgitation and new technical developments are discussed.
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