Related Experiment Video
Updated: Jan 5, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Tricuspid regurgitation due to blood cyst
Cihan Aydın1, Mesut Engin2, Selim Kul1
1Department of Cardiology, Ahi Evren Thoracic and Vascular Surgery Training and Research Hospital, University of Health Sciences, Trabzon, Turkey.
Insights
Cardiac blood cysts, common in newborns, are rare in adults. These endothelial-lined, blood-filled sacs on heart valves typically resolve post-birth but may require surgical removal if complications arise.
Area of Science:
- Cardiovascular Pathology
- Developmental Biology
Background:
- Cardiac blood cysts are blood-filled diverticula lined by endothelium.
- They are frequently observed in stillbirths and newborns, typically resolving within months.
- Their origin is hypothesized to be invaginations of atrial endothelium into atrioventricular valve stroma.
Observation:
- The cysts predominantly originate from the left side of the heart.
- They are commonly located on the atrioventricular valves.
- A potential etiology involves invaginations of atrial endothelium into the valve stroma.
Findings:
- While generally benign and self-resolving, cardiac blood cysts can lead to severe complications in rare instances.
- Complications include embolic stroke, valvular dysfunction, and obstruction of the ventricular outflow tract.
- Surgical intervention is indicated for symptomatic or complicated cardiac blood cysts.
Implications:
- Understanding the developmental origin and natural history of cardiac blood cysts is crucial for accurate diagnosis.
- Early identification and monitoring may prevent severe sequelae.
- Surgical management provides a definitive treatment for complicated cases, improving patient outcomes.
Abstract:
Cardiac blood cysts are confirmed by autopsies in stillbirths but rarely detected in adults. Although cardiac blood cysts are common in newborns, they disappear within a few months after birth. These cysts are blood-filled diverticula surrounded by endothelium. Their possible etiology is invaginations of atrial endothelium into the stroma of atrioventricular valves. Most blood cysts originate from the left side of the heart and are located on the atrioventricular valves. Complication is followed in very little cases, such as embolic stroke, valvular dysfunction, and ventricular outflow system obstruction. The blood cysts leading to complications should be removed surgically.
Related Concept Videos
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation I: Introduction
Mitral Regurgitation I: Introduction
Cardiovascular System Abnormal Findings II: Auscultation
Abnormal Heart Sounds
Gallops:
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Regurgitation IV: Nursing Management

