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18-month clinical evaluation of a copper-containing universal adhesive in non-carious cervical lesions: A
Thalita P Matos1, Mario F Gutiérrez2, Taise A Hanzen1
1School of Dentistry, State University of Ponta Grossa, Ponta Grossa, Brazil.
Objective:
This study aimed to evaluate the addition of copper nanoparticles (CuNp) on the clinical performance of a universal adhesive system used as etch-and-rinse (ER) and self-etch (SE).
Methods:
216 restorations were randomly placed in 36 subjects according to the following groups: ERcu = etch-and-rinse with 0.1% CuNp; ERct = etch-and-rinse without CuNp; SEcu = self-etch with 0.1% CuNp; SEct = self-etch without CuNp. Resin composite was placed incrementally and light-cured. The restorations were evaluated at baseline and 6, 12 and 18 months using the FDI and USPHS criteria. Statistical analyses were performed using appropriate tests (α = 0.05).
Results:
The addition of CuNp did not increase the clinical performance (FDI / USPHS) of the universal adhesive tested after 18-month when applied in the ER mode (p > 0.05). The addition of CuNp in SE restorations increased the retention rate significantly and decreased the marginal discrepancies after 18 months (p < 0.05).
Conclusion:
The clinical performance of universal adhesive was significantly increased when applied in the SE mode with the addition of copper nanoparticles.
Clinical Relevance:
This is the first study that demonstrates a slight improvement in the clinical performance of universal adhesive systems in non-carious cervical lesions when added CuNp in lower concentration.

