Facile preparation of CoMoO₄ nanorods at macroporous carbon hybrid electrocatalyst for non-enzymatic glucose...

Glucose is a popular biosensor target due to its closely with diabetes or hypoglycemia in blood. Designing efficiency electrocatalysts for the determination of glucose is vital to develop glucose detection devices. CoMoO₄, as a kind of bimetallic oxide material, exhibits unique electrochemical properties. 3D macroporous carbon (MPC) has large specific surface area and excellent electrical conductivity, providing an effective support for loading other nano-entities to form novel composite with good synergetic effects. Herein, nanorod-like CoMoO₄ anchored onto MPC support was synthesized for the development of a promising electrochemical sensing platform for glucose. Attributing to the synergic effects between the good electrocatalytic performance of CoMoO₄ nanorods and the extraordinary electrical conductivity of 3D layered MPC, the novel CoMoO₄/MPC composites non-enzymatic sensor shows excellent electrocatalytic performance for oxidation of glucose. Under the optimum conditions, the proposed CoMoO₄/MPC hybrids provided a reliable linear range of 5 × 10^-7 to 1.08 × 10^-4 M with a low limit of detection (0.13 μM) for the detection of glucose. Meanwhile, the CoMoO₄/MPC sensing platform shows fast response time of 1.76 s, good stability and selectivity for detecting glucose. Moreover, this non-enzymatic sensor also has been successfully applied to measure glucose level in human blood samples. Therefore, the developed sensor holds a new promise for the construction of facile and sensitive non-enzymatic glucose analytical platform.