Chest Pain Center Accreditation Is Associated With Improved In-Hospital Outcomes of Acute Myocardial Infarction
Fangfang Fan1, Yuxi Li1, Yan Zhang1
1Department of Cardiology Peking University First Hospital Beijing China.
Insights
Chest pain center (CPC) accreditation improves outcomes for acute myocardial infarction (AMI) patients in China. However, benefits diminish over time, highlighting the need for reaccreditation to maintain care quality.
Area of Science:
- Cardiology
- Healthcare Management
- Public Health
Background:
- Chest pain center (CPC) accreditation is recognized for improving acute myocardial infarction (AMI) management.
- Evidence linking CPC accreditation to improved AMI patient outcomes in China is lacking.
Purpose of the Study:
- To evaluate the impact of CPC accreditation on in-hospital outcomes for AMI patients in China.
- To assess the association between CPC accreditation and major adverse cardiovascular events (MACE) and all-cause death.
Main Methods:
- Retrospective analysis of the CCC-ACS nationwide registry.
- Inclusion of 15,344 AMI patients from 40 CPC-accredited hospitals (pre- and post-accreditation).
- Propensity score matching and multivariate Cox proportional hazards models were used.
Main Results:
- CPC accreditation was associated with significantly lower 7-day MACE and all-cause death rates.
- Multivariate analysis showed decreased risk of MACE (HR: 0.78) and all-cause death (HR: 0.71) post-accreditation.
- A reverse J-shaped trend was observed: benefits peaked in the first year and declined thereafter.
Conclusions:
- CPC accreditation is linked to improved in-hospital outcomes for AMI patients in China.
- The positive effects of accreditation appear to wane over time.
- Regular reaccreditation is crucial for sustaining high-quality AMI care and optimal patient outcomes.
Abstract:
Background Chest pain center (CPC) accreditation plays an important role in the management of acute myocardial infarction (AMI). However, no evidence shows whether the outcomes of AMI patients are improved with CPC accreditation in China. Methods and Results This retrospective analysis is based on a predesigned nationwide registry, CCC-ACS (Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome). The primary outcome was major adverse cardiovascular events (MACE), including all-cause death, reinfarction, stent thrombosis, stroke, and heart failure. A total of 15 344 AMI patients, from 40 CPC-accredited hospitals, were enrolled, including 7544 admitted before and 7800 after accreditation. In propensity score matching, 6700 patients in each group were matched. The incidence of 7-day MACE (6.7% versus 8.0%; P=0.003) and all-cause death (1.1% versus 1.6%; P=0.021) was lower after accreditation. In multivariate adjusted mixed-effects Cox proportional hazards models, CPC accreditation was associated with significantly decreased risk of MACE (hazard ratio: 0.78; 95% CI, 0.68-0.91) and all-cause death (hazard ratio: 0.71; 95% CI, 0.51-0.99). The risk of MACE and all-cause death both followed a reverse J-shaped trend: the risk of MACE and all-cause death decreased gradually after achieving CPC accreditation, with minimal risk occurring in the first year, but increased in the second year and after. Conclusions Based on a large-scale national registry data set, CPC accreditation was associated with better in-hospital outcomes for AMI patients. However, the benefits seemed to attenuate over time, and reaccreditation may be essential for maintaining AMI care quality and outcomes.
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