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Hemodialysis in children: how, when and why
R Chimenz1, C Fede1, V Di Benedetto2
1Department of Human Pathology in Adult and Developmental Age "Gaetano Barresi", Unit of Pediatric Nephrology and Rheumatology with Dialysis, University of Messina, Policlinico "G. Martino" Messina, Italy.
Insights
Chronic dialysis for end-stage renal disease in children is rare but serious. This study compares peritoneal dialysis and hemodialysis, detailing their advantages and disadvantages for pediatric patients.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
Background:
- End-stage renal disease (ESRD) in pediatric populations is uncommon but carries significant mortality and morbidity.
- Primary glomerular disease (GD) is the leading cause of chronic kidney disease (CKD) in children, followed by congenital abnormalities and hereditary disorders.
- Secondary GD, urologic, and metabolic diseases present a higher mortality risk in pediatric ESRD patients compared to primary GD.
Purpose of the Study:
- To compare the treatment options for pediatric end-stage renal disease.
- Specifically analyze and contrast peritoneal dialysis and hemodialysis in children and adolescents.
Main Methods:
- Comparative analysis of peritoneal dialysis and hemodialysis.
- Review of treatment modalities for pediatric ESRD.
Main Results:
- The study focuses on comparing the pros and cons of peritoneal dialysis versus hemodialysis for pediatric ESRD.
- Detailed comparison of outcomes and suitability of each dialysis modality.
Conclusions:
- Understanding the comparative benefits and drawbacks of peritoneal dialysis and hemodialysis is crucial for managing pediatric ESRD.
- Informed treatment choices can potentially improve outcomes and quality of life for affected children.
Abstract:
End-stage renal diseases requiring chronic dialysis are rare in childhood and adolescence, but they are associated with high mortality and impaired quality of life (1, 2). The most common disease that causes chronic kidney disease (CKD) is primary glomerular disease (GD), followed by congenital abnormalities of the kidney and urinary tract, cystic, hereditary or congenital disorders and, more rarely, secondary GD. However, patients with secondary GD, urologic disorders, and metabolic diseases have greater mortality risk than patients with primary GD (3). Here, we focused on the different options of treatment available, and specifically we compared peritoneal dialysis and hemodialysis, showing pros and cons between them.
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