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Acetylcholinesterase and α-glucosidase inhibitory compounds from Callicarpa maingayi

Muhammad A Ado1, M Maulidiani1,2, Intan Safinar Ismail1

  • 1Laboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.

Natural Product Research
|October 22, 2019
PubMed

Keywords:
Callicarpa maingayiacetylcholinesterase inhibitortriterpenoidsα-glucosidase inhibitor

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Indirect-acting cholinergic agonists are agents that interact with the acetylcholinesterase enzyme in the synaptic cleft, preventing the breakdown of acetylcholine into choline and acetate. Consequently, the concentration of acetylcholine in the synaptic cleft increases. These agonists can be classified into reversible and irreversible inhibitors based on their duration of action.
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