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Cardiovascular risk factors are highly overrepresented in Swedish patients with psoriatic arthritis compared with the

A J Landgren1, A Bilberg2, B Eliasson3

  • 1Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Scandinavian Journal of Rheumatology
|October 22, 2019
PubMed

Insights

Patients with psoriatic arthritis (PsA) have higher rates of obesity and hypertension compared to the general population. These cardiovascular risks are particularly pronounced in women with PsA.

Area of Science:

  • Rheumatology
  • Cardiology
  • Public Health

Background:

  • Psoriatic arthritis (PsA) is a chronic inflammatory condition.
  • Cardiovascular disease is a significant comorbidity in PsA patients.
  • Understanding cardiovascular risk factors in PsA is crucial for patient management.

Purpose of the Study:

  • To determine the prevalence of cardiovascular risk factors in PsA patients.
  • To compare these risk factors between PsA patients and the general population.
  • To investigate sex-based differences in cardiovascular risk factors within the PsA cohort.

Main Methods:

  • A questionnaire was distributed to 982 PsA patients at a Swedish Rheumatology Clinic.
  • Data from the Swedish National Public Health Survey were used for general population comparisons.
  • Descriptive statistics and body mass index (BMI) calculations were performed.

Main Results:

  • Obesity (BMI ≥ 30 kg/m²), hypertension, and diabetes were significantly more prevalent in PsA patients (28.6%, 40.3%, 10.5%) than in the general population (16.3%, 24.1%, 6.2%).
  • Obesity was particularly overrepresented in women with PsA.
  • Hypertension and ever smoking were also more prevalent in women with PsA compared to controls.

Conclusions:

  • Obesity is highly overrepresented in patients with psoriatic arthritis.
  • Cardiovascular risk factors, including obesity and hypertension, are more common in PsA patients.
  • Women with PsA exhibit a higher prevalence of obesity, hypertension, and smoking compared to the general population.

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