Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Deconvolution01:20

Deconvolution

518
Deconvolution, also known as inverse filtering, is the process of extracting the impulse response from known input and output signals. This technique is vital in scenarios where the system's characteristics are unknown, and they must be inferred from the observable signals.
Deconvolution involves several mathematical techniques to derive the impulse response. One common approach is polynomial division. In this method, the input and output sequences are treated as coefficients of...
518
Reconstruction of Signal using Interpolation01:10

Reconstruction of Signal using Interpolation

654
Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
654
Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

8.0K
The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...
8.0K
Downsampling01:20

Downsampling

563
When considering a sampled sequence with zero values between sampling instants, one can replace it by taking every N-th value of the sequence. At these integer multiples of N, the original and sampled sequences coincide. This process, known as decimation, involves extracting every N-th sample from a sequence, thereby creating a more efficient sequence.
The Fourier transform of the decimated sequence reveals a combination of scaled and shifted versions of the original spectrum. This...
563
Residuals and Least-Squares Property01:11

Residuals and Least-Squares Property

8.9K
The vertical distance between the actual value of y and the estimated value of y. In other words, it measures the vertical distance between the actual data point and the predicted point on the line
If the observed data point lies above the line, the residual is positive, and the line underestimates the actual data value for y. If the observed data point lies below the line, the residual is negative, and the line overestimates the actual data value for y.
The process of fitting the best-fit...
8.9K
Upsampling01:22

Upsampling

563
Managing signal sampling rates is essential in digital signal processing to maintain signal integrity. A decimated signal, characterized by a reduced frequency range due to its lower sampling rate, can be upsampled by inserting zeros between each sample. This upsampling process expands the original spectrum and introduces repeated spectral replicas at intervals dictated by the new Nyquist frequency. To refine this zero-inserted sequence, it is passed through a lowpass filter with a cutoff...
563

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Solving Inverse Problems using Diffusion with Iterative Colored Renoising.

Transactions on machine learning research·2026
Same author

Conformal Bounds on Full-Reference Image Quality for Imaging Inverse Problems.

Transactions on machine learning research·2026
Same author

Task-Driven Uncertainty Quantification in Inverse Problems via Conformal Prediction.

Computer vision - ECCV ... : ... European Conference on Computer Vision : proceedings. European Conference on Computer Vision·2025
Same author

SURFACE COIL INTENSITY CORRECTION FOR MRI.

Proceedings. IEEE International Symposium on Biomedical Imaging·2025
Same author

Groupwise image registration with edge-based loss for low-SNR cardiac MRI.

Magnetic resonance in medicine·2025
Same author

MRI recovery with self-calibrated denoisers without fully-sampled data.

Magma (New York, N.Y.)·2024
Same journal

2D Ultrasound Elasticity Imaging of Abdominal Aortic Aneurysms Using Deep Neural Networks.

IEEE transactions on computational imaging·2026
Same journal

Scan-Adaptive MRI Undersampling Using Neighbor-based Optimization (SUNO).

IEEE transactions on computational imaging·2026
Same journal

Spatiotemporal Maps for Dynamic MRI Reconstruction.

IEEE transactions on computational imaging·2026
Same journal

A Convergent Generalized Krylov Subspace Method for Compressed Sensing MRI Reconstruction with Gradient-Driven Denoisers.

IEEE transactions on computational imaging·2026
Same journal

IE-GADCI: An End-to-End Incoherence-Enhanced Generative Adversarial Deep Compressive Imaging.

IEEE transactions on computational imaging·2026
Same journal

Using Randomized Nyström Preconditioners to Accelerate Variational Image Reconstruction.

IEEE transactions on computational imaging·2025
See all related articles

Related Experiment Video

Updated: Jan 5, 2026

Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software
08:22

Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software

Published on: July 17, 2018

7.7K

Regularization by Denoising: Clarifications and New Interpretations.

Edward T Reehorst1, Philip Schniter1

  • 1Department of Electrical and Computer Engineering, The Ohio State University, Columbus, OH, 43210.

IEEE Transactions on Computational Imaging
|October 22, 2019
PubMed
Summary
This summary is machine-generated.

This study reveals that Regularization by Denoising (RED) algorithms do not rely on explicit regularization as previously thought. A new Score-Matching by Denoising (SMD) framework is proposed to accurately explain RED algorithms in image recovery.

More Related Videos

Author Spotlight: Using Hyperpolarized Xenon-129 MRI to Study Lung Diseases
09:55

Author Spotlight: Using Hyperpolarized Xenon-129 MRI to Study Lung Diseases

Published on: January 5, 2024

1.7K

Related Experiment Videos

Last Updated: Jan 5, 2026

Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software
08:22

Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software

Published on: July 17, 2018

7.7K
Author Spotlight: Using Hyperpolarized Xenon-129 MRI to Study Lung Diseases
09:55

Author Spotlight: Using Hyperpolarized Xenon-129 MRI to Study Lung Diseases

Published on: January 5, 2024

1.7K

Area of Science:

  • Image processing and computer vision
  • Mathematical imaging
  • Signal processing

Background:

  • Regularization by Denoising (RED) is a powerful image recovery framework.
  • RED algorithms are considered state-of-the-art for image recovery tasks.
  • The theoretical underpinnings of RED algorithms are not fully understood.

Purpose of the Study:

  • To challenge the explicit regularization explanation for RED algorithms.
  • To propose a new framework, Score-Matching by Denoising (SMD), to explain RED.
  • To provide theoretical insights and improved algorithms for RED.

Main Methods:

  • Analyzing the Jacobian symmetry of denoisers used in RED.
  • Developing the Score-Matching by Denoising (SMD) framework.
  • Establishing connections between SMD, kernel density estimation, and minimum mean-squared error denoising.

Main Results:

  • Demonstrating that practical denoisers lack the symmetric Jacobian required for explicit regularization explanation.
  • Showing that SMD accurately explains RED algorithms.
  • Identifying RED algorithms' tendency to seek consensus equilibrium solutions.

Conclusions:

  • Explicit regularization does not explain the success of RED algorithms.
  • The proposed SMD framework offers a more accurate explanation for RED.
  • New algorithms with acceleration and convergence guarantees are derived from the SMD framework.