Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

757
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
757
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

65.2K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
65.2K
The Pituitary Gland01:17

The Pituitary Gland

9.7K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
9.7K
Hormones of the Pituitary Gland01:27

Hormones of the Pituitary Gland

9.1K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
9.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Role of the Surgical Pathologist in the Recognition of Hereditary SDH-Deficient Tumor Syndromes.

Advances in anatomic pathology·2026
Same author

Clinical and molecular features associated with the presence of brain metastases and survival in patients with advanced thyroid cancer.

The oncologist·2026
Same author

Initial Clinical Diagnosis of Intravascular Large B-Cell Lymphoma: Microscopic Disease Involving Minimally Invasive Follicular Thyroid Carcinoma.

Mayo Clinic proceedings·2026
Same author

Well-Differentiated Neuroendocrine Tumors of Lung: A Case Series Supporting the IARC/WHO Common Classification of Neuroendocrine Tumor Nomenclature and Grading.

Endocrine pathology·2026
Same author

Radiotherapy for the management of bone metastases in differentiated thyroid cancer.

Clinical and translational radiation oncology·2026
Same author

Parathyroid Carcinoma Mimicking Thyroid Hyalinizing Trabecular Tumor: A Case Report and Review of Atypical Presentations of Parathyroid Carcinoma.

International journal of surgical pathology·2026

Related Experiment Video

Updated: Jan 5, 2026

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
02:22

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

820

Hypothalamic Endocrine Tumors: An Update.

Sylvia L Asa1,2, Ozgur Mete3,4

  • 1Department of Pathology, Case Western University and University Hospitals, Cleveland, OH 44106, USA. Pathlady01@gmail.com.

Journal of Clinical Medicine
|October 23, 2019
PubMed
Summary

Hypothalamic tumors impact hormonal regulation and metabolic homeostasis. Advances in diagnostic biomarkers improve the classification and understanding of these rare tumors, including gangliocytomas, neurocytomas, and pituicytomas.

Keywords:
endocrinegangliocytomahormoneshypothalamusneurocytomapituicytoma

More Related Videos

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

19.4K
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.1K

Related Experiment Videos

Last Updated: Jan 5, 2026

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
02:22

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

820
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

19.4K
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.1K

Area of Science:

  • Neuroendocrinology
  • Oncology
  • Molecular Biology

Background:

  • The hypothalamus regulates pituitary and endocrine functions through peptide synthesis and secretion.
  • Hypothalamic tumors can cause structural and functional deficits, including hormone hypersecretion.
  • Accurate classification of these tumors is essential for understanding their impact on homeostasis.

Purpose of the Study:

  • To provide an overview of hypothalamic tumors, focusing on their critical role in metabolic homeostasis.
  • To highlight recent advances in the diagnosis and classification of specific hypothalamic tumors.
  • To correlate tumor structure with function using novel biomarkers.

Main Methods:

  • Review of current literature on hypothalamic tumors.
  • Analysis of diagnostic advancements and biomarker applications.
  • Focus on specific tumor types: gangliocytomas, neurocytomas, and pituicytomas.

Main Results:

  • Classification systems for hypothalamic tumors have significantly advanced.
  • Biomarkers are increasingly utilized for precise tumor classification.
  • Structure-function correlations are becoming more accurate, aiding diagnosis.

Conclusions:

  • Hypothalamic tumors require specialized diagnostic approaches due to their unique location and function.
  • Advances in diagnostics, particularly biomarkers, are crucial for managing these tumors.
  • Understanding gangliocytomas, neurocytomas, and pituicytomas is key to improving patient outcomes.